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Microsoft Word - Prachayasittikul_041208_proof.doc
unambiguously distinguished.
The molecular ion [M+1]+ of either 10 (R1 = C6H5, R2 = iso-C4H9) or 11 (R1 = C6H5, R2 = iso-C4H9) showed the same value as 407, but the daughter fragmenta- tion patterns should be [...] the Gabriel synthesis (Solo- mons and Fryhle, 2008) of primary amine to give pyridazine-3,6-dione (9). Pathway 2, initial nucleophilic substitution takes place on ester followed by the second substitution [...] 3.37 (d, 1HC, J = 8 Hz), 3.65 (dd, 1HB, J = 8 Hz), 3.84 (s, 3H, CO2CH3), 4.86 (d, 1HA, J = 8 Hz), 5.9 (s, 1H, furyl), 6.31 (d, 1H, J = 4 Hz, furyl), 7.19-7.45 (m, 10H, 2C6H5); IR
υmax (nujol) 3419,3134 …