eldorado.tu-dortmund.de/server/api/core/bitstreams/3e5d7478-60a8-4c65-b574-2459fd9abf7f/content
factor which contains a CRE sequence in the promotor region (Thiel et al., 2005; Thonpho et
al., 2010; Xing and Quinn, 1993). The glucogenic pathway is the reversal of glycolysis except
for four steps [...] mutations in the G6PC gene are highly associated
with glycogen storage disease (GSD)(Chou et al., 2010). As stated before, glucose can also be
produced from triglyceride-derived glycerol. Glycerol kinase [...] ƭƛLJƛŘǎΦ ¢ƘŜ ǘŜNJƳ ǿƘƛŎƘ ŘŜǎŎNJƛōŜǎ ǘƘƛǎ LJƘŜƴƻƳŜƴƻƴ ƛǎ άŜŎǘƻLJƛŎ Ŧŀǘ ŀŎŎdzƳdzƭŀǘƛƻƴέ
(Bugianesi et al., 2010; Byrne, 2013). It is estimated that NAFLD will represent the most
frequent indication for liver t …