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A PRACTICAL OVERVIEW OF QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP
fluvoxamine maleate (Pharco Pharmaceuticals, Alexan- dria, A.R.E.) were used and dissolved in isotonic (0.9 % NaCl) saline solution im-
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EXCLI Journal 2011;10:290-302 – ISSN 1611-2156 Received: October 18 [...] flu- voxamine (10, 20 mg/kg) (groups 5, 6), im- piramine (10, 20 mg/kg) (groups 7, 8) or saline (group 9, control) once daily orally for 2 days before and just before lipopoly- saccharide injection (200 mg/kg [...] the end of the experi- ments, brains and livers were removed, washed with ice-cold saline solution (0.9 % NaCl) and stored at -80 ºC for further de- termination of biochemical parameters. They were homogenised …